Fallout 4 by Bethesda is a huge game, in particular if you play it on Survival mode. In Fallout 4 Survival Mode, fast travel is disabled and the total weight you can carry is severely limited. Everywhere you want to go, you’ll have to go there the old-fashioned way: on foot (or in a Vertibird, when you’ve unlocked that possibility). Also, since Fallout 4 is the item collector’s dream, everything can be taken and everything is useful. So, inventory management is king.